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Anti-Cortisol Binding Globulin Antibody
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- BACKGROUND
Application 
| WB, IHC-P, ICC |
|---|---|
| Primary Accession | P08185 |
| Host | Rabbit |
| Reactivity | Human |
| Clonality | Polyclonal |
| Format | Lyophilized |
| Description | Rabbit IgG polyclonal antibody for Corticosteroid-binding globulin(SERPINA6) detection. Tested with WB, IHC-P, ICC in Human. |
| Reconstitution | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
| Gene ID | 866 |
|---|---|
| Other Names | Corticosteroid-binding globulin, CBG, Serpin A6, Transcortin, SERPINA6, CBG |
| Calculated MW | 45141 MW KDa |
| Application Details | Immunocytochemistry , 0.5-1 µg/ml, Human, - Immunohistochemistry(Paraffin-embedded Section), 0.5-1 µg/ml, Human, By Heat Western blot, 0.1-0.5 µg/ml, Human |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells. |
| Protein Name | Corticosteroid-binding globulin |
| Contents | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human Cortisol Binding Globulin(102-120aa ETEIHQGFQHLHQLFAKSD). |
| Purification | Immunogen affinity purified. |
| Cross Reactivity | No cross reactivity with other proteins |
| Storage | At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing. |
| Sequence Similarities | Belongs to the serpin family. |
| Name | SERPINA6 |
|---|---|
| Synonyms | CBG |
| Function | Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. |
| Cellular Location | Secreted. |
| Tissue Location | Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Corticosteroid-binding globulin(CBG), also known as Serpin A6 is a protein that in humans is encoded by the SERPINA6 gene. It is mapped 14q32.13. This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events.
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